Article
Weight gain after liver transplantation and the insertion/deletion polymorphism of the angiotensin-converting enzyme gene.
Transplantation - 27 May 2005
Toniutto Pierluigi, Fabris Carlo, Minisini Rosalba, Apollonio Luca, Fumo Elisabetta, Caldato Maya, Smirne Carlo, Pirisi Mario
Abstract excerpt
BACKGROUND: Subjects who carry the D allele of the angiotensin-converting enzyme (ACE) gene have higher plasma and tissue angiotensin II levels, possibly concurrent with the development of obesity. In transplant recipients, treatment with calcineurin antagonists would magnify these effects. The present study verifies whether the allelic variants of ACE are a factor involved in excess weight gain after liver...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.