Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence against a blood derived origin for transforming growth factor beta induced protein in corneal disorders caused by mutations in the TGFBI gene.

Molecular vision - 27 Jun 2007

Karring Henrik, Valnickova Zuzana, Thøgersen Ida B, Hedegaard Chris J, Møller-Pedersen Torben, Kristensen Torsten, Klintworth Gordon K, Enghild Jan J

Abstract excerpt

PURPOSE: Several inherited corneal disorders in humans result from mutations in the transforming growth factor beta induced gene (TGFBI), which encodes for the extracellular transforming growth factor beta induced protein (TGFBIp) that is one of the most abundant proteins in the cornea. We previously reported a significant amount of TGFBIp in plasma by immunoblotting using the only TGFBIp antiserum (anti-p68(beta...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Artifacts
Share to Cornea

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Corneal Diseases

Share to Epitopes

Share to Extracellular Matrix Proteins

Share to Immune Sera

Share to Immunoblotting

Share to Transforming Growth Factor beta

Source

Open in PubMed Open full text

Identifiers

PMID: 17653042
PMCID: PMC2776536

Genes

TGFBI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence against a blood derived origin for transforming growth factor beta induced protein in corneal disorders caused by mutations in the TGFBI gene.PMID 17653042Read ↗

A unique TGFBI protein in granular corneal dystrophy types 1 and 2.Semantic proximity Read ↗

Clinical and genetic aspects of the TGFBI-associated corneal dystrophies.Semantic proximity Read ↗

Protein Analysis of the TGFBIR124H Mouse Model Gives Insight into Phenotype Development of Granular Corneal Dystrophy.Semantic proximity Read ↗

LASIK surgery of granular corneal dystrophy type 2 patients leads to accumulation and differential proteolytic processing of transforming growth factor beta-induced protein (TGFBIp).Semantic proximity Read ↗

Transforming growth factor beta induced protein accumulation in granular corneal dystrophy type III (Reis-Bücklers dystrophy). Identification by mass spectrometry in 15 year old two-dimensional protein gels.Semantic proximity Read ↗

Proteomic Analysis of Amyloid Corneal Aggregates from TGFBI-H626R Lattice Corneal Dystrophy Patient Implicates Serine-Protease HTRA1 in Mutation-Specific Pathogenesis of TGFBIp.Semantic proximity Read ↗

TGFBIp/betaig-h3 protein: a versatile matrix molecule induced by TGF-beta.Semantic proximity Read ↗

Structural and Functional Implications of Human Transforming Growth Factor β-Induced Protein, TGFBIp, in Corneal Dystrophies.Semantic proximity Read ↗

Pathogenesis and treatments of TGFBI corneal dystrophies.Semantic proximity Read ↗

Comparison of two phenotypically distinct lattice corneal dystrophies caused by mutations in the transforming growth factor beta induced (TGFBI) gene.Semantic proximity Read ↗

Composition and proteolytic processing of corneal deposits associated with mutations in the TGFBI gene.Semantic proximity Read ↗

A novel mutation in transforming growth factor-beta induced protein (TGFβIp) reveals secondary structure perturbation in lattice corneal dystrophy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.