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Article

A novel mutation in transforming growth factor-beta induced protein (TGFβIp) reveals secondary structure perturbation in lattice corneal dystrophy.

The British journal of ophthalmology - 1 Oct 2011

Lakshminarayanan Rajamani, Vithana Eranga N, Chai Shu-Ming, Chaurasia Shyam S, Saraswathi Padhmanaban, Venkatraman Anandalaksmi, Rojare Camille, Venkataraman Divya, Tan Donald, Aung Tin, Beuerman Roger W, Mehta Jodhbir S

Abstract excerpt

BACKGROUND: To describe mutations in the transforming growth factor-beta induced (TGFBI) gene in Asian patients with Bowman's membrane as well as stromal corneal dystrophies, and to elucidate their structural implications, using model peptides. METHODS: Twenty-two unrelated Asian families were ex...

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Source

Identifiers

PMID: 21835759
DOI: 10.1136/bjophthalmol-2011-300651

Genes

TGFBI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21835759-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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