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Article

Structural and Functional Implications of Human Transforming Growth Factor β-Induced Protein, TGFBIp, in Corneal Dystrophies.

Structure (London, England : 1993) - 7 Nov 2017

García-Castellanos Raquel, Nielsen Nadia Sukusu, Runager Kasper, Thøgersen Ida B, Lukassen Marie V, Poulsen Ebbe T, Goulas Theodoros, Enghild Jan J, Gomis-Rüth F Xavier

Abstract excerpt

A major cause of visual impairment, corneal dystrophies result from accumulation of protein deposits in the cornea. One of the proteins involved is transforming growth factor β-induced protein (TGFBIp), an extracellular matrix component that interacts with integrins but also produces corneal deposits when mutated. Human TGFBIp is a multi-domain 683-residue protein, which contains one CROPT domain and four FAS1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28988748
DOI: 10.1016/j.str.2017.09.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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