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Article

A method for detecting effect of beneficial mutations in natural populations of Drosophila melanogaster.

Genetical research - 1 Oct 1991

Koga A, Kusakabe S, Tajima F, Takano T, Harada K, Mukai T

Abstract excerpt

An experimental method is proposed for detecting the effects of positive natural selection on DNA polymorphisms. Since beneficial mutations are expected to increase in frequency faster than neutral mutations, variants which have reached high frequencies in a relatively short period could be linked to some beneficial mutation. D. melanogaster has a cosmopolitan polymorphic inversion -In(2L)t- whose age in some...

Topics

Alleles
Animals
Base Sequence
DNA
Drosophila melanogaster
Female
Genes, Lethal
Genes, Recessive
Genetic Techniques
Haplotypes
Male
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Polymorphism, Genetic

Restriction Mapping

Selection, Genetic

Source

Identifiers

PMID: 1765262
DOI: 10.1017/s0016672300029803

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1765262-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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