Article
Hitchhiking mapping: a population-based fine-mapping strategy for adaptive mutations in Drosophilamelanogaster.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 2002
Harr Bettina, Kauer Max, Schlötterer Christian
Abstract excerpt
The identification of genes contributing to the adaptation of local populations is of great biological interest. In an attempt to characterize functionally important differences among African and non-African Drosophila melanogaster populations, we surveyed neutral microsatellite variation in an 850-kb genomic sequence. Three genomic regions were identified that putatively bear an adaptive mutation associated with...
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