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Article

Biochemical characterization of USP7 reveals post-translational modification sites and structural requirements for substrate processing and subcellular localization.

The FEBS journal - 1 Aug 2007

Fernández-Montalván Amaury, Bouwmeester Tewis, Joberty Gerard, Mader Robert, Mahnke Marion, Pierrat Benoit, Schlaeppi Jean-Marc, Worpenberg Susanne, Gerhartz Bernd

Abstract excerpt

Ubiquitin specific protease 7 (USP7) belongs to the family of deubiquitinating enzymes. Among other functions, USP7 is involved in the regulation of stress response pathways, epigenetic silencing and the progress of infections by DNA viruses. USP7 is a 130-kDa protein with a cysteine peptidase core, N- and C-terminal domains required for protein-protein interactions. In the present study, recombinant USP7 full...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17651432
DOI: 10.1111/j.1742-4658.2007.05952.x

Genes

USP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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