Article
Mutations in a newly identified Drosophila melanogaster gene, mago nashi, disrupt germ cell formation and result in the formation of mirror-image symmetrical double abdomen embryos.
Development (Cambridge, England) - 1 Sept 1991
Boswell R E, Prout M E, Steichen J C
Abstract excerpt
The mago nashi (mago) locus is a newly identified strict maternal effect, grandchildless-like, gene in Drosophila melanogaster. In homozygous mutant mago females reared at 17 degrees C, mago+ function is reduced, the inviable embryos lack abdominal segments and 84-98% of the embryos die. In contr...
Topics
- Abdomen
- Animals
- Cell Polarity
- Drosophila melanogaster
- Embryo, Nonmammalian
- Genes
- Germ Cells
- Microscopy, Electron
- Morphogenesis
- Mutation
- Oocytes
- Phenotype