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Contribution of genetics and epigenetics to progression of kidney fibrosis

23 Aug 2013

Abstract excerpt

Chronic kidney disease (CKD) which can lead to end-stage renal failure remains a principal challenge in Nephrology. While mechanistic studies provided extensive insights into the common pathways of fibrogenesis which underlie the progression of CKD, these pre-clinical studies fail to fully explain the vastly different progression slopes of individual patients. Recent studies provide evidence that genetic...

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PMID: 23975750
DOI: 10.1093/ndt/gft025

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