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Article

Evidence for common ancestral origin of a recurring BRCA1 genomic rearrangement identified in high-risk Hispanic families.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2007

Weitzel Jeffrey N, Lagos Veronica I, Herzog Josef S, Judkins Thaddeus, Hendrickson Brant, Ho Jason S, Ricker Charité N, Lowstuter Katrina J, Blazer Kathleen R, Tomlinson Gail, Scholl Tom

Abstract excerpt

BACKGROUND: Large rearrangements account for 8% to 15% of deleterious BRCA mutations, although none have been characterized previously in individuals of Mexican ancestry. METHODS: DNA from 106 Hispanic patients without an identifiable BRCA mutation by exonic sequence analysis was subjected to mul...

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Source

Identifiers

PMID: 17646271
DOI: 10.1158/1055-9965.EPI-07-0198

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17646271-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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