Article
Gene expression profiling in human gastric mucosa infected with Helicobacter pylori.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2007
Hofman Véronique J, Moreilhon Chimène, Brest Patrick D, Lassalle Sandra, Le Brigand Kevin, Sicard Dominique, Raymond Josette, Lamarque Dominique, Hébuterne Xavier A, Mari Bernard, Barbry Pascal Jp, Hofman Paul M
Abstract excerpt
Pathogenic mechanisms associated with Helicobacter pylori infection enhance susceptibility of the gastric epithelium to carcinogenic conversion. We have characterized the gene expression profiles of gastric biopsies from 69 French Caucasian patients, of which 43 (62%) were infected with H. pylori. The bacterium was detected in 27 of the 42 antral biopsies examined and in 16 of the 27 fundic biopsies. Infected...
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