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Single-cell transcriptomic profiling uncovers cellular complexity and microenvironment in gastric tumorigenesis associated with Helicobacter pylori

2023-11-25

Abstract excerpt

<h4>Background: </h4> Helicobacter pylori ( H. pylori) infection is a key initiating factor in the Correa cascade of gastric carcinogenesis, but the comprehensive understanding of the pathogenic mechanisms underlying H. pylori -induced gastric cancer (GC) remains elusive. Here, we generated a single-cell atlas of gastric tumorigenesis comprising 18 specimens of gastritis, intestinal metaplasia and GC with or witho...

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Literature Corpus work
877d2171-9966-5237-9493-9e40d40889bf
DOI
10.21203/rs.3.rs-3641851/v1
Open publication

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Single-cell transcriptomic profiling uncovers cellular complexity and microenvironment in gastric tumorigenesis associated with Helicobacter pyloriDOI 10.21203/rs.3.rs-3641851/v1
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