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Multi-omics reveals microbiome, host gene expression, and immune landscape in gastric carcinogenesis

19 Feb 2022

Abstract excerpt

To date, there has been no multi-omic analysis characterizing the intricate relationships between the intragastric microbiome and gastric mucosal gene expression in gastric carcinogenesis. Using multi-omic approaches, we provide a comprehensive view of the connections between the microbiome and host gene expression in distinct stages of gastric carcinogenesis (i.e., healthy, gastritis, cancer). Our integrative...

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PMID: 35265820
DOI: 10.1016/j.isci.2022.103956

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