Article
Inflammatory gene profiles in gastric mucosa during Helicobacter pylori infection in humans.
Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2004
Wen Sicheng, Felley Christian P, Bouzourene Hanifa, Reimers Mark, Michetti Pierre, Pan-Hammarström Qiang
Abstract excerpt
Helicobacter pylori infection is associated with an inflammatory response in the gastric mucosa, ultimately leading to cellular hyperproliferation and malignant transformation. Hitherto, only expression of a single gene, or a limited number of genes, has been investigated in infected patients. cDNA arrays were therefore used to establish the global pattern of gene expression in gastric tissue of healthy subjects...
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