APOE epsilon 4 allele, cognitive dysfunction, and obstructive sleep apnea in children.

doi:10.1212/01.wnl.0000265818.88703.83

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Article

APOE epsilon 4 allele, cognitive dysfunction, and obstructive sleep apnea in children.

Neurology - 17 Jul 2007

Gozal David, Capdevila Oscar Sans, Kheirandish-Gozal Leila, Crabtree Valerie McLaughlin

Abstract excerpt

BACKGROUND: Obstructive sleep apnea (OSA) in children is associated with severity-dependent changes in neurocognitive functioning. However, the severity of OSA accounts for only approximately 40% of the variance in cognitive performance. Thus, genetic determinants of individual susceptibility may...

Topics

Alleles
Apolipoprotein E4
Child
Child, Preschool
Cognition Disorders
Female
Humans
Male
Sleep Apnea, Obstructive

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