Article
Experimental approaches to evaluate the contributions of candidate cis-regulatory mutations to phenotypic evolution.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Rebeiz Mark, Williams Thomas M
Abstract excerpt
Elucidating the molecular bases by which phenotypic traits have evolved provides a glimpse into the past, allowing the characterization of genetic changes that cumulatively contribute to evolutionary innovations. Historically, much of the experimental attention has been focused on changes in protein-coding regions that can readily be identified by the genetic code for translating gene coding sequences into...
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