Article
CPC: assess the protein-coding potential of transcripts using sequence features and support vector machine.
Nucleic acids research - 1 Jul 2007
Kong Lei, Zhang Yong, Ye Zhi-Qiang, Liu Xiao-Qiao, Zhao Shu-Qi, Wei Liping, Gao Ge
Abstract excerpt
Recent transcriptome studies have revealed that a large number of transcripts in mammals and other organisms do not encode proteins but function as noncoding RNAs (ncRNAs) instead. As millions of transcripts are generated by large-scale cDNA and EST sequencing projects every year, there is a need for automatic methods to distinguish protein-coding RNAs from noncoding RNAs accurately and quickly. We developed a...
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