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Article

The efficiency of nonsense-mediated mRNA decay is an inherent character and varies among different cells.

European journal of human genetics : EJHG - 1 Nov 2007

Linde Liat, Boelz Stephanie, Neu-Yilik Gabriele, Kulozik Andreas E, Kerem Batsheva

Abstract excerpt

Nonsense-mediated mRNA decay (NMD) is a mechanism, which selectively degrades transcripts carrying premature termination codons (PTCs) and a variety of physiologic transcripts containing NMD-inducing features. In a recent study, we have found variable NMD efficiency among nasal epithelial cells obtained from cystic fibrosis (CF) patients. This variability was found for CF transmembrane conductance regulator...

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Identifiers

PMID: 17625509
DOI: 10.1038/sj.ejhg.5201889

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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