Article
Clinical outcomes of breast cancer in carriers of BRCA1 and BRCA2 mutations.
The New England journal of medicine - 12 Jul 2007
Rennert Gad, Bisland-Naggan Shantih, Barnett-Griness Ofra, Bar-Joseph Naomi, Zhang Shiyu, Rennert Hedy S, Narod Steven A
Abstract excerpt
BACKGROUND: Some features of breast cancer in women with a BRCA1 mutation suggest that hereditary breast cancer has a poor outcome. We conducted a national population-based study of Israeli women to determine the influence, if any, of a BRCA1 or a BRCA2 mutation on the prognosis in breast cancer. METHODS: We obtained data on all incident cases of invasive breast cancer that were diagnosed from January 1, 1987, to...
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