Article
Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jan 2008
Chetrit Angela, Hirsh-Yechezkel Galit, Ben-David Yehuda, Lubin Flora, Friedman Eitan, Sadetzki Siegal
Abstract excerpt
PURPOSE: To evaluate the long-term survival of ovarian cancer (OvC) patients in total and by BRCA1/2 mutation status. PATIENTS AND METHODS: In a nationwide case-control study on OvC conducted in Israel between 1994 and 1999, 779 Jewish women with epithelial invasive OvC were tested for the three Ashkenazi Jewish founder mutations in BRCA1 (185delAG; 5382insC) and BRCA2 (6174delT) genes and followed for survival...
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