Article
Xanthine oxidoreductase polymorphisms: influence in blood pressure and oxidative stress levels.
Pharmacogenetics and genomics - 1 Aug 2007
Chaves Felipe J, Corella Dolores, Blesa Sebastian, Mansego Maria L, Marín Pablo, Portoles Olga, Sorlí Jose V, González-Albert Verónica, Tormos Mari C, García-García Ana B, Sáez Guillermo, Redon Josep
Abstract excerpt
OBJECTIVES: Oxidative stress can modulate blood pressure levels in different models. Xanthine oxidoreductase is one of the enzymes producing free radicals in the cardiovascular system, and it can contribute to the increment of the oxidative stress and, consequently, blood pressure. We analyzed the association between the -337GA and 565+64CT polymorphisms of the xanthine oxidoreductase gene with blood pressure and...
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