Article
The bromodomain protein LEX-1 acts with TAM-1 to modulate gene expression in C. elegans.
Molecular genetics and genomics : MGG - 1 Nov 2007
Tseng Rong-Jeng, Armstrong Kristin R, Wang Xiaodong, Chamberlin Helen M
Abstract excerpt
In many organisms, repetitive DNA serves as a trigger for gene silencing. However, some gene expression is observed from repetitive genomic regions such as heterochromatin, suggesting mechanisms exist to modulate the silencing effects. From a genetic screen in C. elegans, we have identified mutat...
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