Article
Genetic intratumour heterogeneity in high-grade brain tumours is associated with telomere-dependent mitotic instability.
Neuropathology and applied neurobiology - 1 Aug 2007
Glanz C, Rebetz J, Stewénius Y, Persson A, Englund E, Mandahl N, Mertens F, Salford L G, Widegren B, Fan X, Gisselsson D
Abstract excerpt
Glioblastoma multiforme (GBM) and other high-grade brain tumours are typically characterized by complex chromosome abnormalities and extensive intratumour cytogenetic heterogeneity. The mechanisms behind this diversity have been little explored. In this study, we analysed the pattern of chromosom...
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