Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Podocalyxin increases the aggressive phenotype of breast and prostate cancer cells in vitro through its interaction with ezrin.

Cancer research - 1 Jul 2007

Sizemore Steven, Cicek Muzaffer, Sizemore Nywana, Ng Kwok Peng, Casey Graham

Abstract excerpt

Podocalyxin is an anti-adhesive transmembrane sialomucin that has been implicated in the development of more aggressive forms of breast and prostate cancer. The mechanism through which podocalyxin increases cancer aggressiveness remains poorly understood but may involve the interaction of podocal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytoskeletal Proteins
Share to MAP Kinase Signaling System
Share to Matrix Metalloproteinase 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Matrix Metalloproteinase 9

Share to Neoplasm Invasiveness

Share to Phosphatidylinositol 3-Kinases

Share to Prostatic Neoplasms

Share to Sialoglycoproteins

Source

Identifiers

PMID: 17616675
DOI: 10.1158/0008-5472.CAN-06-3575

Genes

MMP1
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17616675-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Podocalyxin increases the aggressive phenotype of breast and prostate cancer cells in vitro through its interaction with ezrin.PMID 17616675Read ↗

Galectin-9 signaling drives breast cancer invasion through matrixSemantic proximity Read ↗

Overexpression of the Pluripotent Stem Cell Marker Podocalyxin in Prostate CancerSemantic proximity Read ↗

Moesin-dependent cytoskeleton remodelling is associated with an anaplastic phenotype of pancreatic cancer.Semantic proximity Read ↗

Tumor invasion in the absence of epithelial-mesenchymal transition: Podoplanin-mediated remodeling of the actin cytoskeletonSemantic proximity Read ↗

Elevated expression of podocalyxin is associated with lymphatic invasion, basal-like phenotype, and clinical outcome in axillary lymph node-negative breast cancer.Semantic proximity Read ↗

Sorting nexin 9 negatively regulates invadopodia formation and function in cancer cellsSemantic proximity Read ↗

Podoplanin interaction with caveolin-1 promotes tumour cell migration and invasionSemantic proximity Read ↗

Requirement of Podocalyxin in TGF-Beta Induced Epithelial Mesenchymal TransitionSemantic proximity Read ↗

ZEB1 enhances transendothelial migration and represses the epithelial phenotype of prostate cancer cells.Semantic proximity Read ↗

The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration.Semantic proximity Read ↗

Syndecan-1 (CD138), Carcinomas and EMTSemantic proximity Read ↗

A Mutation in the Carbohydrate Recognition Domain Drives a Phenotypic Switch in the Role of Galectin-7 in Prostate Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.