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Syndecan-1 (CD138), Carcinomas and EMT

19 Apr 2021

Abstract excerpt

Cell surface proteoglycans are known to be important regulators of many aspects of cell behavior. The principal family of transmembrane proteoglycans is the syndecans, of which there are four in mammals. Syndecan-1 is mostly restricted to epithelia, and bears heparan sulfate chains that are capable of interacting with a large array of polypeptides, including extracellular matrix components and potent mediators of...

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PMID: 33921767
DOI: 10.3390/ijms22084227

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