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Article

APOE and AD concordance in twin pairs as predictors of AD in first-degree relatives.

Neurology - 8 Feb 2000

Steffens D C, Plassman B L, Helms M J, Welsh-Bohmer K A, Newman T T, Breitner J C

Abstract excerpt

OBJECTIVE: To examine the independent effects of the APOE genotype (APOE) and concordance for AD in twin pairs on the occurrence of AD in first-degree relatives. BACKGROUND: Studies of twins have been undertaken to investigate the influence of genes in a variety of conditions, including AD. A previous study, performed before reports linking APOE to AD, demonstrated an increase in AD among first-degree relatives...

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Source

Identifiers

PMID: 10680788
DOI: 10.1212/wnl.54.3.593

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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