Article
Genetic susceptibility of newborn daughters to oxidative stress.
Toxicology letters - 30 Jul 2007
Decordier Ilse, De Bont Kelly, De Bock Kirsten, Mateuca Raluca, Roelants Mathieu, Ciardelli Roberta, Haumont Dominique, Knudsen Lisbeth E, Kirsch-Volders Micheline
Abstract excerpt
A central question in risk assessment is whether newborns' susceptibility to mutagens is different from that of adults. Therefore we investigated whether genotype and/or the DNA strand break repair phenotype in combination with the MN assay would allow estimation of the relative sensitivity of a newborn as compared to his mother for oxidative DNA damage. We compared the in vitro genetic susceptibility for H2O2 in...
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