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Article

Deletions in chromosome 4 differentially associated with the development of cervical cancer: evidence of slit2 as a candidate tumor suppressor gene.

Human genetics - 1 Aug 2007

Singh Ratnesh Kumar, Indra Dipanjana, Mitra Sraboni, Mondal Ranajit Kumar, Basu Partha Sarathi, Roy Anup, Roychowdhury Susanta, Panda Chinmay Kumar

Abstract excerpt

The aim of this study was to locate the candidate tumor suppressor genes (TSGs) loci in the chromosomal 4p15-16, 4q22-23 and 4q34-35 regions associated with the development of uterine cervical carcinoma (CA-CX). Deletion mapping of the regions by microsatellite markers identified six discrete areas with high frequency of deletions, viz. 4p16.2 (D1: 40%), 4p15.31 (D2: 35-38%), 4p15.2 (D3: 37-40%), 4q22.2 (D4:...

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Share to Carcinoma, Squamous Cell
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 4

Share to Genes, Tumor Suppressor

Share to Intercellular Signaling Peptides and Proteins

Share to Papillomavirus Infections

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Share to Uterine Cervical Neoplasms

Source

Identifiers

PMID: 17609981
DOI: 10.1007/s00439-007-0375-6

Genes

SLIT2
ROBO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deletions in chromosome 4 differentially associated with the development of cervical cancer: evidence of slit2 as a candidate tumor suppressor gene.PMID 17609981Read ↗

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