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Article

Ubiquitination of human immunodeficiency virus type 1 Gag is highly dependent on Gag membrane association.

Journal of virology - 1 Sept 2007

Jäger Stefanie, Gottwein Eva, Kräusslich Hans-Georg

Abstract excerpt

Ubiquitin is important for the release of human immunodeficiency virus 1 (HIV-1) and several other retroviruses. All major domains of the HIV-1 Gag protein are monoubiquitinated, but the modifying machinery and the function of HIV-1 Gag ubiquitination remain unclear. Here, we show that the induction of a late budding arrest by mutation of the HIV-1 PTAP motif or by specific inhibition of selected ESCRT components...

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Topics

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Share to Cell Membrane
Share to gag Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Products, gag

Share to Protein Processing, Post-Translational

Share to Protein Transport

Share to Ubiquitins

Share to Virus Replication

Source

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Identifiers

PMID: 17609272
DOI: 10.1128/JVI.00044-07
PMCID: PMC1951426

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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