Article
The joint allele-frequency spectrum in closely related species.
Genetics - 1 Sept 2007
Chen Hua, Green Richard E, Pääbo Svante, Slatkin Montgomery
Abstract excerpt
We develop the theory for computing the joint frequency spectra of alleles in two closely related species. We allow for arbitrary population growth in both species after they had a common ancestor. We focus on the case in which a single chromosome is sequenced from one of the species. We use classical diffusion theory to show that, if the ancestral species was at equilibrium under mutation and drift and a...
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