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Article

Nonparametric coalescent inference of mutation spectrum history and demography.

Proceedings of the National Academy of Sciences of the United States of America - 25 May 2021

DeWitt William S, Harris Kameron Decker, Ragsdale Aaron P, Harris Kelley

Abstract excerpt

As populations boom and bust, the accumulation of genetic diversity is modulated, encoding histories of living populations in present-day variation. Many methods exist to decode these histories, and all must make strong model assumptions. It is typical to assume that mutations accumulate uniformly across the genome at a constant rate that does not vary between closely related populations. However, recent work...

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Identifiers

PMID: 34016747
DOI: 10.1073/pnas.2013798118
PMCID: PMC8166128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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