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Article

Molecular beacon-style hybridization assay for quantitative analysis of surface invasive cleavage reactions.

Analytical chemistry - 1 Aug 2007

Lockett Matthew R, Shortreed Michael R, Smith Lloyd M

Abstract excerpt

A hybridization-based FRET format for the scoring of SNPs in surface invasive cleavage reactions is described. In early versions of the surface invasive cleavage reaction, dual-labeled oligonucleotides, containing both a quencher moiety and a fluorophore, were attached to the substrate. The invasive cleavage reaction cleaved the DNA strand between the two, resulting in an increase in fluorescence signal due to...

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PMID: 17595056
DOI: 10.1021/ac070424c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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