Article
Functional polymorphisms of the GSTT-1 gene do not predict the severity of acute pancreatitis in the United States.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Jan 2007
Bhat Yasser M, Papachristou Georgios I, Park James S, Lamb Janette, Slivka Adam, Whitcomb David C
Abstract excerpt
BACKGROUND/AIM: Acute pancreatitis (AP) is an inflammatory response to pancreatic injury that is clinically classified as mild AP or severe AP, depending on specific criteria. Rahman and colleagues [Gastroenterology 2004;126:1312-1322] reported that genetic variation in the glutathione S-transferase theta-1 gene (GSTT-1) is associated with susceptibility and severity of AP in England. Our aim was to determine...
Topics
- Acute Disease
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Female
- Genetic Predisposition to Disease
- Genotype
- Glutathione Transferase
- Humans
- Male
- Middle Aged
- Pancreatitis
- Pennsylvania