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Article

Effects of long-term ethanol consumption and Aldh1b1 depletion on intestinal tumourigenesis in mice.

The Journal of pathology - 1 Apr 2017

Müller Mike F, Zhou Ying, Adams David J, Arends Mark J

Abstract excerpt

Ethanol and its metabolite acetaldehyde have been classified as carcinogens for the upper aerodigestive tract, liver, breast, and colorectum. Whereas mechanisms related to oxidative stress and Cyp2e1 induction seem to prevail in the liver, and acetaldehyde has been proposed to play a crucial role in the upper aerodigestive tract, pathological mechanisms in the colorectum have not yet been clarified. Moreover, all...

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Identifiers

PMID: 28026023
DOI: 10.1002/path.4869

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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