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Article

Renin-angiotensin system and nitric oxide synthase gene polymorphisms in relation to stroke.

American journal of hypertension - 1 Jul 2007

Henskens Léon H, Kroon Abraham A, van der Schouw Yvonne T, Schiffers Paul M, Grobbee Diederick E, de Leeuw Peter W, Bots Michiel L

Abstract excerpt

BACKGROUND: There is ample evidence that genetic factors contribute to cardiovascular disease risk. The present study aimed to assess the relation between polymorphisms of the angiotensin II type 1 receptor (AGTR1 A(1166)C) and endothelial nitric oxide synthase (NOS3 G(894)T) and the risk of stroke. METHODS: We performed a case-cohort study on all first fatal and nonfatal stroke events (n = 74) and a 10% random...

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Source

Identifiers

PMID: 17586411
DOI: 10.1016/j.amjhyper.2007.02.012

Genes

AGTR1
NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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