Article
Endothelial nitric oxide synthase gene interactions and the risk of ischaemic stroke.
Acta neurologica Scandinavica - 1 Jan 2005
Szolnoki Z, Havasi V, Bene J, Komlósi K, Szöke D, Somogyvári F, Kondacs A, Szabó M, Fodor L, Bodor A, Gáti I, Wittman I, Melegh B
Abstract excerpt
OBJECTIVE: Endothelial nitric oxide synthase (eNOS), which produces NO, plays an important role in the endothelial function under a wide range of physiological conditions. eNOS exon 7 polymorphism (Glu298Asp, G894T) has been considered to influence the risk of coronary artery disease. Alone, however, it has not been shown to be a genetic risk factor for ischaemic stroke. With the assumption of additive...
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