Article
Chy-3 mice are Vegfc haploinsufficient and exhibit defective dermal superficial to deep lymphatic transition and dermal lymphatic hypoplasia.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Aug 2007
Dellinger Michael T, Hunter Robert J, Bernas Michael J, Witte Marlys H, Erickson Robert P
Abstract excerpt
Recent advances in molecular lymphology and lymphatic phenotyping techniques in small animals offer new opportunities to delineate mutant mouse models. Chy-3 mutant mice were originally named for their chylous ascites, but the underlying lymphatic disorder was not defined. We now re-examined these mice and applied advanced genotyping and lymphatic phenotyping techniques to pinpoint the specific lymphatic defect...
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