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Article

Genetics of lymphatic anomalies.

The Journal of clinical investigation - 1 Mar 2014

Brouillard Pascal, Boon Laurence, Vikkula Miikka

Abstract excerpt

Lymphatic anomalies include a variety of developmental and/or functional defects affecting the lymphatic vessels: sporadic and familial forms of primary lymphedema, secondary lymphedema, chylothorax and chylous ascites, lymphatic malformations, and overgrowth syndromes with a lymphatic component. Germline mutations have been identified in at least 20 genes that encode proteins acting around VEGFR-3 signaling but...

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Source

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Identifiers

PMID: 24590274
DOI: 10.1172/JCI71614
PMCID: PMC3938256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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