Article
Mirk/Dyrk1B in cancer.
Journal of cellular biochemistry - 1 Oct 2007
Friedman Eileen
Abstract excerpt
Mirk/Dyrk1B is a member of a conserved family of serine/threonine kinases which are activated by intramolecular tyrosine phosphorylation, and which mediate differentiation in different tissues-Mirk in skeletal muscle, Dyrk1A in the brain, etc. One role of Mirk in skeletal muscle differentiation is to block cycling myoblasts in the G0 quiescent state by modification of cell cycle regulators, while another role of...
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