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Article

Hereditary thrombophilia and recurrent pregnancy loss: a systematic review and meta-analysis.

Human reproduction (Oxford, England) - 20 Apr 2021

Liu Xiaoling, Chen Yan, Ye Changxiang, Xing Dexiu, Wu Rong, Li Fang, Chen Lizhang, Wang Tingting

Abstract excerpt

STUDY QUESTION: Is there an association between hereditary thrombophilia in pregnant women and risk of recurrent pregnancy loss (RPL)? SUMMARY ANSWER: Pregnant women with hereditary thrombophilia have an increased risk of RPL, especially for pregnant women with the G1691A mutation of the factor V Leiden (FVL) gene, the G20210A mutation of the prothrombin gene (PGM), and deficiency of protein S (PS). WHAT IS KNOWN...

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Abortion, Habitual
Mutation
Odds Ratio
Pregnancy
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33575779
DOI: 10.1093/humrep/deab010

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