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Article

Limited family structure and BRCA gene mutation status in single cases of breast cancer.

JAMA - 20 Jun 2007

Weitzel Jeffrey N, Lagos Veronica I, Cullinane Carey A, Gambol Patricia J, Culver Julie O, Blazer Kathleen R, Palomares Melanie R, Lowstuter Katrina J, MacDonald Deborah J

Abstract excerpt

CONTEXT: An autosomal dominant pattern of hereditary breast cancer may be masked by small family size or transmission through males given sex-limited expression. OBJECTIVE: To determine if BRCA gene mutations are more prevalent among single cases of early onset breast cancer in families with limited vs adequate family structure than would be predicted by currently available probability models. DESIGN, SETTING,...

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Source

Identifiers

PMID: 17579227
DOI: 10.1001/jama.297.23.2587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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