Article
Identification of Mycobacterium avium pathogenicity island important for macrophage and amoeba infection.
Proceedings of the National Academy of Sciences of the United States of America - 26 Jun 2007
Danelishvili Lia, Wu Martin, Stang Bernadette, Harriff Melanie, Cirillo Suat L G, Cirillo Stuart, Cirillo Jeffrey D, Cirillo Jeffrey, Bildfell Robert, Arbogast Brian, Bermudez Luiz E
Abstract excerpt
The ability to infect macrophages is a common characteristic shared among many mycobacterial species. Mycobacterium avium, Mycobacterium tuberculosis, and Mycobacterium kansasii enter macrophages, using the complement receptors CR1, CR3, CR4, and the mannose receptor. To identify M. avium genes and host cell pathways involved in the bacterial uptake by macrophages, we screened a M. avium transposon mutant library...
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