Article
Logic regression for analysis of the association between genetic variation in the renin-angiotensin system and myocardial infarction or stroke.
American journal of epidemiology - 1 Feb 2007
Kooperberg Charles, Bis Joshua C, Marciante Kristin D, Heckbert Susan R, Lumley Thomas, Psaty Bruce M
Abstract excerpt
Recent developments in genetic sequencing technology now make it possible to genotype large numbers of single nucleotide polymorphisms (SNPs) in large samples. Many association studies using SNP data are now being carried out. Typically, these observational studies establish whether certain haplotypes or individual SNPs are associated with a health outcome. Few methods exist for finding interaction effects among...
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