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Article

Testing SNPs and sets of SNPs for importance in association studies.

Biostatistics (Oxford, England) - 1 Jan 2011

Schwender Holger, Ruczinski Ingo, Ickstadt Katja

Abstract excerpt

A major goal of genetic association studies concerned with single nucleotide polymorphisms (SNPs) is the detection of SNPs exhibiting an impact on the risk of developing a disease. Typically, this problem is approached by testing each of the SNPs individually. This, however, can lead to an inaccurate measurement of the influence of the SNPs on the disease risk, in particular, if SNPs only show an effect when...

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Identifiers

PMID: 20601626
DOI: 10.1093/biostatistics/kxq042
PMCID: PMC3006123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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