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Article

In vitro selection and characterization of human immunodeficiency virus type 2 with decreased susceptibility to lopinavir.

Antimicrobial agents and chemotherapy - 1 Sept 2007

Masse Sherie, Lu Xiaozhi, Dekhtyar Tatyana, Lu Liangjun, Koev Gennadiy, Gao Feng, Mo Hongmei, Kempf Dale, Bernstein Barry, Hanna George J, Molla Akhteruzzaman

Abstract excerpt

Lopinavir (LPV)-ritonavir has demonstrated durable antiviral activity in human immunodeficiency virus type 1 (HIV-1)-infected antiretroviral-naïve and protease inhibitor (PI)-experienced patients. However, information on LPV activity against HIV-2 and the patterns of mutations in HIV-2 in response to selection by LPV is limited. The activity of LPV against three strains of HIV-2 was assessed and compared to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17576848
DOI: 10.1128/AAC.00146-07
PMCID: PMC2043247

Genes

CBL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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