Article
Dactylone inhibits epidermal growth factor-induced transformation and phenotype expression of human cancer cells and induces G1-S arrest and apoptosis.
Cancer research - 15 Jun 2007
Fedorov Sergey N, Shubina Larisa K, Bode Ann M, Stonik Valentin A, Dong Zigang
Abstract excerpt
The marine natural chamigrane-type sesquiterpenoid, dactylone, is closely related to secondary metabolites of some edible species of red algae. In the present study, the effect of dactylone was tested on the mouse skin epidermal JB6 P+ Cl41 cell line and its stable transfectants as well as on sev...
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