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Article

The effect of branch lengths on phylogeny: an empirical study using highly conserved orthologs from mammalian genomes.

Molecular phylogenetics and evolution - 1 Oct 2007

Hughes Austin L, Friedman Robert

Abstract excerpt

Phylogenetic analyses were applied to 269 families of putative orthologs represented by a single member in the genomes of human, mouse, dog, and chicken. Five methods were used: maximum parsimony (NP), neighbor-joining (NJ) with Poisson and Gamma distances; and maximum likelihood (ML) with JTT and JTT+gamma models. When applied to the concatenated sequence of all families, all methods strongly supported a tree in...

Topics

Animals
Base Sequence
Chickens
Conserved Sequence
Dogs
Evolution, Molecular
Genetic Variation
Genome
Humans
Mammals
Mice
Phylogeny

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Homology, Nucleic Acid

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Identifiers

PMID: 17574446
DOI: 10.1016/j.ympev.2007.04.022
PMCID: PMC2756227

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