Article
Reduction of proliferative heterogeneity of CHEF18 Chinese hamster cell line during the progression toward tumorigenicity.
In vitro cellular & developmental biology : journal of the Tissue Culture Association - 1 Dec 1991
Rainaldi G, Pinto B, Piras A, Vatteroni L, Simi S, Citti L
Abstract excerpt
Doubling time and generation time represent two parameters by which the proliferation of cultured mammalian cells can be monitored. In this study we report the characterization of CHEF18 Chinese hamster cell line during the progression toward tumorigenicity by analysis of doubling time and generation time. The two parameters reveal that the proliferation was initially different, indicating the presence of a...
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