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Article

GNAS transcripts in skeletal progenitors: evidence for random asymmetric allelic expression of Gs alpha.

Human molecular genetics - 15 Aug 2007

Michienzi Stefano, Cherman Natasha, Holmbeck Kenn, Funari Alessia, Collins Michael T, Bianco Paolo, Robey Pamela Gehron, Riminucci Mara

Abstract excerpt

Activating mutations of the Gsalpha gene, encoded by the guanine nucleotide-binding protein, alpha stimulating (GNAS) locus located on chromosome 20q13, underlie different clinical phenotypes characterized by skeletal lesions [fibrous dysplasia (FD) of bone], extraskeletal diseases (mainly endocrine hyperfunction and skin hyperpigmentation) and variable combinations thereof [the McCune-Albright syndrome (MAS)]....

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Source

Identifiers

PMID: 17566083
DOI: 10.1093/hmg/ddm139

Genes

GNAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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