Article
The histopathology of fibrous dysplasia of bone in patients with activating mutations of the Gs alpha gene: site-specific patterns and recurrent histological hallmarks.
The Journal of pathology - 1 Jan 1999
Riminucci M, Liu B, Corsi A, Shenker A, Spiegel A M, Robey P G, Bianco P
Abstract excerpt
Gs alpha mutations and histopathology have been analysed in a series of 13 patients with fibrous dysplasia (FD) of bone, including 12 patients with the McCune-Albright syndrome (MAS) and one patient with monostotic FD. Activating mutations (either R201C or R201H) of the gene encoding the alpha subunit of the stimulatory G protein, Gs, were detected in all cases, including the case of monostotic FD, using a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.